Research

A team of researchers from S. N. Bose National Centre for Basic Sciences (SNBNCBS), Kolkata, and Institute of Nano Science and Technology (INST), Mohali, both institute of Department of Science and Technology (DST) as well as from SRM University, Amaravati, has now demonstrated that a specially designed metal-free organic porous material, prepared from 2,4,6-tris(4-aminophenyl)-1,3,5-triazine (TTT) and  4,8-dioxo-4,8-dihydrobenzo[1,2-b:4,5-b’]dithiophene-2,6-dicarbaldehyde (DHTD) linkers, named as TTT-DHTD.

A multi-institutional study was carried out, co-ordinated by scientists from Aryabhatta Research Institute of Observational Sciences (ARIES), Nainital, an autonomous institution of the Department of Science and Technology (DST), to capture the most recent 12-year optical outbursts (periodic/quasi-periodic pattern) between 2015 and 2019.

GP 1102 also stood out for its mineral profile. It recorded the highest calcium and magnesium concentrations among the tested lines, combining strong protein performance with high levels of two important nutrients. Calcium content across the collection ranged from 8.04 to 33.49 mg per 100 grams, while magnesium ranged from 24.41 to 60.59 mg per 100 grams.

The researchers first confirmed that the treated flies had developed relevant biological and behavioural changes before testing the infrared method. The flies showed impaired movement, disturbances in activity patterns and degeneration of dopaminergic neurons.

Human tissues contain an extracellular matrix, or ECM, consisting of proteins, carbohydrates and other biological molecules surrounding cells. Far from serving only as a structural framework, the extracellular matrix provides biochemical and mechanical signals that influence how cells grow, differentiate and behave.

Autophagy is a fundamental biological process through which cells remove damaged or unnecessary components. Material identified for removal is enclosed inside specialised double-membrane structures called autophagosomes. These structures subsequently deliver their contents for degradation and recycling, allowing useful molecular components to be reused.

In a study that included CHIME collaborators at the Raman Research Institute (RRI), an autonomous institute of the Department of Science and Technology (DST), the CHIME telescope has shown, for the first time, that it can detect the faint glow of hydrogen gas from deep in the universe’s past using only its own data.

The research involved scientists and clinicians associated with Pt. B.D. Sharma Post Graduate Institute of Medical Sciences in Rohtak, Maulana Azad Medical College in New Delhi, JSS Medical College in Mysuru, All India Institute of Medical Sciences New Delhi, Pacific Medical College and Hospital in Udaipur and Pathkind National Reference Laboratory in Gurugram.

The study was published in the September 2026 issue of Molecular Pharmaceutics by the American Chemical Society. It combines spectroscopic experiments, thermodynamic analysis, molecular docking and biological testing to examine how cotarnine and its derivatives behave in a biomedical environment.