Research

On further study, the researchers found that Polymerase GammaA in 50% of the tested adPEO patients was highly ubiquitylated. However it was possible to reverse the process of ubiquitylation either by removing MITOL itself or by genetically modifying the site Polymerase GammaA in adPEO patients that gets highly ubiquitylated by MITOL. Speaking to India Science Wire, the leader of the team, Dr. Sagar Sengupta, said, “It will be interesting to test in future whether the reactivation of Polymerase Gamma A can actually be carried out in the patients using mitochondrial genome editing techniques”.

The study, published in ‘EMBO Molecular Medicine, was led by Amit Singh, Associate Professor and Wellcome Trust-DBT India Alliance Senior Fellow at the Department of Microbiology & Cell Biology and Centre for Infectious Diseases Research (CIDR), and Govindasamy Mugesh, Professor at the Department of Inorganic and Physical Chemistry.

he Indian Institute of Horticultural Research (IIHR) in Bengaluru has developed five new chilli hybrids, which it says are resistant to the devastating leaf curl virus (LCV) that afflicts the crop.

In a new study geared in this direction, researchers at Bengaluru-based Indian Institute of Science (IISc)’s Centre for Ecological Sciences (CES) and collaborators have demonstrated that the venom of Russell’s vipers was dramatically different in composition and toxicity based on geographical location, though the commercial antivenom treatment for Russell’s viper venom works as marketed for most populations of this snake, except the ones in North India.

The wireless product called Giga Mesh could enable telecom operators deploy quality, high-speed rural telecom infrastructure at 5 times lower cost. Rural connectivity customers and defence customers who have already signed up for pilots will soon witness the demonstration of this product by Astrome.

A team of researchers at the Department of Biotechnology’s Hyderabad-based National Institute of Animal Biotechnology (DBT-NIAB) has developed a new technique to detect the presence of an antibiotic called Oxytetracycline (OTC) in milk samples.

A number of key technologies were developed indigenously to accomplish this major feat, which included the use of indigenously developed ‘NAVIC’ receiver for time synchronisation between the transmitter and receiver modules, and gimbal mechanism systems instead of bulky large-aperture telescopes for optical alignment, it said.

Scientists have found a method to mimic nature’s own process of reducing carbon dioxide in the atmosphere, namely photosynthesis, to capture excess carbon dioxide in the atmosphere. This artificial photosynthesis (AP) harnesses solar energy and converts the captured carbon dioxide to carbon monoxide (CO), which can be used as a fuel for internal combustion engines.